some assignment block is visible in design time ( the assignment block already appears in "Displayed Assignment blocks" area), however it is missing in runtime.

Set a breakpoint on CL_PRD01OV_MATERIALOV_IMPL->DETACH_STATIC_OVW_VIEWS , open the product overview page again:
totally 65 assignment blocks as static views are fetched from runtime repository,

then they are filtered in cl_crm_uiu_prod_tools_layout=>get_views_to_display:

You can debug the code to check why your assignment block is determined to be hidden in the runtime ( put into internal table lt_detach )
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